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Join a Study on Early Life Stress & Depression

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About the Study

This research is being conducted at McLean Hospital in Belmont, MA. The goal is to better understand how experiences during adolescence affect brain activity related to depression and stress response in adulthood in women. The study explores how the brain responds to depression or early life stress, which may help researchers identify individuals at risk sooner and develop more targeted therapies for women with these experiences.

Quick Facts

Local Study

1 in-person visit takes place at McLean Hospital, Belmont MA and 3 remote visits

Females Only

Assigned female at birth

Time

Four sessions totaling approximately 13 hours

Compensation

Up to $690 for completed participation

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Who Can Participate?
  • Are a woman (assigned female at birth)
  • Can attend three remote visits and one in-person visit at McLean Hospital in Belmont, MA
  • Have a history of depression (current or past), with or without experiences of abuse before age 19

What the Study Involves:

Complete clinical screening (structured interview and questionnaires) remotely over Zoom.
Undergo an MRI brain scan
Participate in follow‑up phone interviews at 6 and 12 months
You can get a complimentary interactive, 3D image of your MRI brain scan.

Participation is voluntary and confidential. No medical claims are made.

Compensation and Benefits:

Qualified participants can earn up to $690 including an Amazon Gift Card. Your contribution helps advance scientific understanding of how childhood stress shapes brain health and depression risk in adult women.

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FAQ

We’ve pulled together some basics to help you get started

Who qualifies for this study?

Women who have a history of depression (current or past), with or without experiences of abuse before age 19.

Does it cost anything to participate?

No, there is no cost to join the study. All required study procedures are provided at no charge.

Where is the study being conducted?

The study visits are held at McLean Hospital in Belmont, Massachusetts.

Is my information confidential?

Yes. Your participation and all information you provide will be kept confidential and used only for research purposes.

What will happen if I participate in the study?

Participation in this research study involves:

- Phone screen (30-minute phone call): questions about your medical & psychiatric history, drug/alcohol use, and childhood experiences
- Screening survey
- Assessment session
(3 hours over Zoom): review consent form, fill out surveys, and meet with a clinician
- MRI session
at McLean Hospital (5.5-6 hours in person): 2 brain scans, blood draws, surveys, and a stress response task
- 6- and 12- month follow-ups
(1-hour phone call): speak with a clinician and fill out surveys